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Mechanistically, Se treatment significantly increases aspartate content, the initial precursor for caffeine, potentially providing sufficient substrates for caffeine biosynthesis ( Notably, exogenous Se application does not always enhance alkaloid content of tea, as the Se regulatory role on alkaloids is closely associated with tea-growing seasons

SLC7A11 serves as an independent indicator of poor prognosis in acute myeloid leukemia (101) and an independent risk factor in ovarian cancer (102)

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KD therapy could be a novel, nontoxic, cost-effective adjuvant therapy for cancer patients that exploits tumor metabolic weaknesses beyond glucose/insulin signaling

Several studies conducted in the last 20 years have demonstrated that the aqueous constituents present in tomatoes inhibit the aggregation of blood platelets, both in vitro and in vivo